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Nature 437, 461 (22 September
2005) | doi: 10.1038/437461b
Lack of lab notes casts doubt on RNA researcher's
results
Ichiko Fuyuno, Tokyo
Abstract
Japanese university has been unable
to confirm its professor's results.
A respected Japanese scientist who failed to produce laboratory
notebooks confirming his published results now faces a furore over
the credibility of his findings.
On 13 September, the University of Tokyo's School of Engineering
held a press conference to say that Kazunari Taira, a professor at
the school who specializes in RNA research, had not provided raw
data to verify his team's results. The RNA Society of Japan has
also questioned some of Taira's methods.
Last year, the RNA Society of Japan began receiving letters from
scientists in Japan and elsewhere saying that they could not repeat
Taira's results. In April the society asked the University of
Tokyo to examine 12 of Taira's papers published between 1998 and
2004.
The university set up a committee of internal and external experts
to examine four papers out of the 12, including two published in
Nature (H. Kawasaki and K. Taira
Nature 423, 838−842;
2003 and
Nature 431, 211−217;
2004) — the first paper had already been retracted (
Nature 426, 100;
2003) and the second corrected (
Nature 431, 878;
2004). The panel asked Taira to submit samples and notebooks
relating to the experiments, but the researcher in his lab who ran
the experiments did not have them. The researcher had stored data
in a computer, some of which had since been scrapped.
The university press release said that "the investigation committee
so far could not confirm the credibility of research results
because it could not confirm the existence of clear data to support
those results". It has asked Taira to do the experiments again, and
will produce a final report by March 2006.
Taira says that not taking notes was "not common sense" and was
regrettable. All the other researchers working with him keep notes,
he says.
But Taira says that the oversight does not mean his methods are
wrong, and says other groups have used his technique to publish
findings. He also says that other researchers' notebooks back up
some of the experiments. He now requires his researchers and
students to get their notes signed by a third party.
Kimihiko Hirao, head of the School of Engineering, says that,
unlike many countries, Japan doesn't have independent bodies to
monitor scientific wrongdoing. "It's time to consider establishing
a third-party regulatory system," he says.
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